SPRL1 Polyclonal Antibody, 50ul Contamination Detection & Removal Frequent amplification of this gene

Frequent amplification of this gene has been found in human tumors

Mutations in this gene cause hyperlipoproteinemia type IB

MARCH1 (membrane associated ring-CH-type finger 1) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases

The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections

Contains 3 EF-hand domains

SPRL1 Polyclonal Antibody, 50ul Contamination Detection & Removal Frequent amplification of this geneBelongs to the SPARC family.,Contains 1 EF hand domain.,Contains 1 follistatin like domain.,Contains 1 Kazal like domain.,tissue specificity: Highly expressed in lymph node, brain, heart, lung, skeletal muscle, ovary, small intestine, and colon, with lower levels in placenta, pancreas, testis, spleen, and thymus, and no expression in kidney, liver, and peripheral blood leukocytes.,