Triclabendazole D5 Hydrochloride Cell Physiol Biochem

Cell Physiol Biochem

Chemical Name: 3-{1-[(3

PNU-120596 increases the channel mean open time ofα7 nAChRs but has no effect on ion selectivity and relatively little

8)/b20-11+

Na/c1-17-10-3-8(4-11(5-10)18-2)12-6-9(13)7-19(14

Triclabendazole D5 Hydrochloride Cell Physiol BiochemTriclabendazole is an anthelmintic and fasciolicidal, binding to beta tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and