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Topotecan Hydrochloride Catalog No.:M9750-2 (2012) Mol Cancer Ther

Topotecan Hydrochloride Catalog No.:M9750-2 (2012) Mol Cancer Ther

Name: Topotecan Hydrochloride Catalog No.:M9750-2 (2012) Mol Cancer Ther
Brand: kentjenerator.com
SKU: 84674310548
Price: 75.00 USD
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Topotecan Hydrochloride Catalog No.:M9750-2 (2012) Mol Cancer TherTopocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid

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Description

(2012) Mol Cancer Ther

Nishikawa K

35-hexamethyl-11

Effect of KAD-1229

activates PKA

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