Eletriptan hydrobromide - CAS# 177834-92-3 Catalog No.:M10984-2 JX06 (1-10 μM

JX06 (1-10 μM

InChiKey: MLRAMCAHIWHWRM-UHFFFAOYSA-N

Caspase activation in whole cells was followed by monitoring the increase in activity against Ac-DEVD-amc following Ionomycin treatment

1-dimethylethyl)sulfonamido)-N-(5-(trifluoromethyl)pyridin-2-yl)cyclohexane-1-carboxamide

4R)-4-benzyl-2-hydroxy-4-{[(1S

Eletriptan hydrobromide - CAS# 177834-92-3 Catalog No.:M10984-2 JX06 (1-10 μMEletriptan Hydrobromide is a triptan with specific affinity for the 5 hydroxytriptamine1B 1D receptor. Eletriptan hydrobromide binds to and acts at serotonin 5 HT1B receptors located on intracranial blood vessels which leads to vasoconstriction. This drug may also exert its effects by binding to and activating 5 HT 1D receptors on sensory nerve endings in the trigeminal system, which results in the inhibition of pro inflammatory neuropeptide release.