DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Polymorphisms in this protein appear

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance

The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

NONO (non-POU domain containing

DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Polymorphisms in this protein appearPPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.