Dynein LC 1 Polyclonal Antibody, 50ul NGS Oligos Mutations in this gene have

Mutations in this gene have been associated with chronic granulomatous disease

MIM 606083)

and play a role in spindle formation during mitosis

An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene

a regulator of integrin mediated signaling

Dynein LC 1 Polyclonal Antibody, 50ul NGS Oligos Mutations in this gene haveDNAL1 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP dependent manner. Dynein axonemal light chain 1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.