BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates However| this gene product contains

However| this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus| and a transposase domain at the C-terminus| suggesting that it may belong to the family of DNA-mediated transposons in human

their beta chains are unique and confer biological specificity

Several related pseudogenes have also been identified

The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain

possibly by inhibition of mRNA stabilization

BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates However| this gene product containsBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.