Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis Alternatively spliced transcript variant encoding

Alternatively spliced transcript variant encoding distinct isoforms have been observed

Among its related pathways are Metabolism and Alzheimers disease

lung and kidney

The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity

This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation

Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis Alternatively spliced transcript variant encodingThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.