Myt 1(Phospho Ser83) Polyclonal Antibody, 50ul Capsule Filter Pimase (DNA) subunit 1 ncoded

Pimase (DNA) subunit 1 ncoded by PRIM1 is the small

Dysregulation of this gene has been associated with the growth and progression of certain cancers

Serine palmitoyltransferase| which consists of two different subunits| is the key enzyme in sphingolipid biosynthesis

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

have been associated with papillary thyroid carcinoma

Myt 1(Phospho Ser83) Polyclonal Antibody, 50ul Capsule Filter Pimase (DNA) subunit 1 ncodedThis gene encodes a member of the serine threonine protein kinase family. The encoded protein is a membrane associated kinase that negatively regulates the G2 M transition of the cell cycle by phosphorylating and inactivating cyclin dependent kinase 1. The activity of the encoded protein is regulated by polo like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.