UT2 Rabbit Polyclonal Antibody, 20ul Filtration In humans| two ubiquitous plastin

In humans| two ubiquitous plastin isoforms (L and T) have been identified

This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation

Disruption of this gene may be associated with cerebral palsy

The protein product is 91% identical to ubiquitin-conjugating enzyme E2N| a multi-exon gene product

and encoding different isoforms of gamma 2 chain

UT2 Rabbit Polyclonal Antibody, 20ul Filtration In humans| two ubiquitous plastinThe protein encoded by this gene belongs to the urea transporter family. In mammalian cells urea is the chief end product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.