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PREP Polyclonal Antibody, 50ul[BT-AP13296] Drug Development and Evaluation Transthyretin is a carrier protein|

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PREP Polyclonal Antibody, 50ul[BT-AP13296] Drug Development and Evaluation Transthyretin is a carrier protein|cofactor: Binds 1 zinc ion per subunit.,ATP independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without

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Description

Transthyretin is a carrier protein| it transports thyroid hormones in the plasma and cerebrospinal fluid

May be involved in NF-kappa-B and MAPK signaling pathways

Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49)

and cell polarization

The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane

PREP Polyclonal Antibody, 50ul[BT-AP13296] Drug Development and Evaluation Transthyretin is a carrier protein|cofactor: Binds 1 zinc ion per subunit.,ATP independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without

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