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PKD2 Polyclonal Antibody, 20ul[BT-AP07230] Yeast Expression cyclosporin A

SKU: 95428470751

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PKD2 Polyclonal Antibody, 20ul[BT-AP07230] Yeast Expression cyclosporin APKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in

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Description

cyclosporin A

This subunit associates with the beta 1 subunit to form a fibronectin receptor

Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription regulatory region sequence-specific DNA binding

Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member

Expression of this receptor is found in vascular endothelial cells

PKD2 Polyclonal Antibody, 20ul[BT-AP07230] Yeast Expression cyclosporin APKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in

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