YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation and share DNA-binding

and share DNA-binding

SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies

Three transcript variants that encode distinct proteins have been identified

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis

YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation and share DNA-bindingThe protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.