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ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes a protein

SKU: 95051887523

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ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes a proteinThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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Description

This gene encodes a protein containing a coiled-coil (CC) domain| a tubulin-tyrosine ligase (TTL) domain| and a tetratrico peptide repeat (TPR) domain

Multiple transcript variants encoding different isoforms have been found for CABLES1

subcellular location:Seems to be excluded from nucleoli

while the paper/plastic packaging keeps them sterile

POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al

ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes a proteinThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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