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UCH-L1 Polyclonal Antibody, 100ul[BT-AP09398] Polyclonal Antibodies Isoform 1 mediates NK cell

SKU: 94854277208

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UCH-L1 Polyclonal Antibody, 100ul[BT-AP09398] Polyclonal Antibodies Isoform 1 mediates NK cellUbiquitin carboxyl terminal hydrolase isozyme L1 encoded by UCHL1 belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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Description

Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway

The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain

Mammalian mitochondrial ribosomal protein L 4 (39S ribosomal protein L4 mitochondrial) is encoded by nuclear gene MRPL4 and help in protein synthesis within the mitochondrion

and faintly in placenta

The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells

UCH-L1 Polyclonal Antibody, 100ul[BT-AP09398] Polyclonal Antibodies Isoform 1 mediates NK cellUbiquitin carboxyl terminal hydrolase isozyme L1 encoded by UCHL1 belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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