Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Immune suppressive molecule that inhibits

Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed: 30580966)

Contains 1 MIB/HERC2 domain

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions

but is upregulated upon activation of lymphocytes

Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Immune suppressive molecule that inhibitsComponent of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium