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GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube AQP4 encodes a member of

SKU: 92018095395

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GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube AQP4 encodes a member ofThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.

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Description

AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells

Yeast two-hybrid studies found ULK1/2 associated with modulators of the endocytic pathway

They are known to bind several kinases of intermediary metabolism

A mutation in this gene has been associate

It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion

GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube AQP4 encodes a member ofThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.

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