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CD141 Polyclonal Antibody, 100ul sgRNA customized design The protein is thought to

SKU: 91158034018

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CD141 Polyclonal Antibody, 100ul sgRNA customized design The protein is thought toThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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Description

The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4

both of which are found in proteins involved in cell signaling

The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked

The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells

This gene is a member of the alpha interferon gene cluster on chromosome 9

CD141 Polyclonal Antibody, 100ul sgRNA customized design The protein is thought toThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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