Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays Reduced expression of this gene

Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane| suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions

such as controlling the regulation of the cell cycle at the G1 to S phase transition

Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes

including the BRCA1-A complex and the BRISC complex

Activity of this protein is also involved in the generation of reactive oxygen species

Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays Reduced expression of this geneCDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium dependent cell cell adhesion. Mature cadherin proteins are composed of a large N terminal extracellular domain, a single membrane spanning domain, and a small, highly conserved C terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity