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CEAM7 Polyclonal Antibody, 100ul Immunology An alternative open reading frame

SKU: 9039636340

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CEAM7 Polyclonal Antibody, 100ul Immunology An alternative open reading frameThis gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.

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Description

An alternative open reading frame product of this gene has been described in PMID:10399963

which are involved in a range of biological activities including cell growth

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In the C-terminal section

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CEAM7 Polyclonal Antibody, 100ul Immunology An alternative open reading frameThis gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.

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