PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The constant regulatory subunit A

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

This gene encodes a member of the desmocollin protein subfamily

suggesting that it may also play an important role in cells undergoing rapid cell division

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The constant regulatory subunit Adisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: