Separase(Phospho Ser801) Polyclonal Antibody, 20ul Purification Has narrower substrate selectivity compared
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Separase(Phospho Ser801) Polyclonal Antibody, 20ul Purification Has narrower substrate selectivity comparedStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which
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