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p15 Polyclonal Antibody, 50ul Isothermal Amplification Alternative splicing of this gene

SKU: 86967201859

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p15 Polyclonal Antibody, 50ul Isothermal Amplification Alternative splicing of this geneCDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically

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Description

Alternative splicing of this gene results in several transcript variants encoding three different isoforms

This gene encodes one of the three enolase isoenzymes found in mammals

a small protein identical in sequence to the C-terminus of myosin light chain kinase

The protein encoded by this gene belongs to the ETS family of transcription factors

The protein encoded by this gene| along with its paralog (scaffold attachment factor B1)| is a repressor of estrogen receptor alpha

p15 Polyclonal Antibody, 50ul Isothermal Amplification Alternative splicing of this geneCDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically

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