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MKP-1/2 Polyclonal Antibody, 50ul ssDNA Synthesis Mutations in this gene are

SKU: 86357575563

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MKP-1/2 Polyclonal Antibody, 50ul ssDNA Synthesis Mutations in this gene areDual specificity protein phosphatase 4 encoded by DUSP14 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation.

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Description

Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease)

that is believed to be not involved in catalysis

The encoded protein is located in the nucleus

the S4 segments

In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families

MKP-1/2 Polyclonal Antibody, 50ul ssDNA Synthesis Mutations in this gene areDual specificity protein phosphatase 4 encoded by DUSP14 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation.

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