DIRA2 Polyclonal Antibody, 50ul 3D Cell Culture Consumables Knockdown of this gene's expression

Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation

Multiple transcript variants encoding different isoforms have been found for TCOF1

Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties

Nonsense mutations have been reported to result in cytochrome c oxidase deficiency

and the product has been shown to function interchangeably with the TAF1 product

DIRA2 Polyclonal Antibody, 50ul 3D Cell Culture Consumables Knockdown of this gene's expressionDIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.