SETBP Rabbit Polyclonal Antibody, 20ul Immunology transmembrane protein

transmembrane protein

which is characterized by skeletal dysplasia with generalized limb bone shortening

preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus

SETBP Rabbit Polyclonal Antibody, 20ul Immunology transmembrane proteinThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.