PAK gamma Polyclonal Antibody, 50ul[BT-AP12762] Serum This gene is located in

This gene is located in a cluster on chromosome 10 with five other closely related genes

The encoded protein mediates sodium-| chloride-| and pH-independent transport of L-isomers of neutral amino acids| including leucine| phenylalanine| valine and methionine

The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes

This gene encodes a regulatory subunit of the SMG1 complex

The gene product of the E

PAK gamma Polyclonal Antibody, 50ul[BT-AP12762] Serum This gene is located inThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role