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TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Vacuum Filter The protein can activate the

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TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Vacuum Filter The protein can activate theThe NF kappa B (NFKB) complex of proteins is inhibited by I kappa B (IKB) proteins which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain

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Description

The protein can activate the complement pathway in association with MASPs and sMAP

Alternative splicing of this gene results in several products of undetermined function

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen

Allelic variants of this gene are associated with microcephaly

while maintaining suppression of p53 transactivation and apoptotic functions

TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Vacuum Filter The protein can activate theThe NF kappa B (NFKB) complex of proteins is inhibited by I kappa B (IKB) proteins which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain

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