ANGP2 Polyclonal Antibody, 50ul Organelle Studies Interacts with CUL4B and DDB1

Interacts with CUL4B and DDB1

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

a MAM domain and a C-terminal GPI-anchoring site

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane

ANGP2 Polyclonal Antibody, 50ul Organelle Studies Interacts with CUL4B and DDB1The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.