MARH9 Polyclonal Antibody, 50ul Endonucleases & Exonucleases EphA3 (Hek4)

EphA3 (Hek4)

CDH26 encodes a cadherin domain-containing protein whose specific function has not yet been determined

Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells

The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome

which belongs to the fibulin family

MARH9 Polyclonal Antibody, 50ul Endonucleases & Exonucleases EphA3 (Hek4)MARCH9 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004