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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance suggesting a role of this

SKU: 82381542017

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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance suggesting a role of thisFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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Description

suggesting a role of this cytokine in the pathogenesis of the disease

This family member is most abundant in muscle but is expressed in all tissues

This gene encodes a large protein that forms a structural component of the nuclear matrix

which may play a role in the signal transduction pathway mediated by multiple Wnt proteins

This protein has been found to bind to p47phox

FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance suggesting a role of thisFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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