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CTDP1 Rabbit Polyclonal Antibody, 20ul Human Genome Knockout Libraries POLE4 is a histone-fold protein

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CTDP1 Rabbit Polyclonal Antibody, 20ul Human Genome Knockout Libraries POLE4 is a histone-fold proteinThis gene encodes a protein which interacts with the carboxy terminus of the RAP74 subunit of transcription initiation factor TFIIF and functions as a phosphatase that processively dephosphorylates the C terminus of POLR2A (a subunit of RNA polymerase II) making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced

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Description

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner

The Sec23 homolog B

which is a cap binding protein complex that consists of three subunits: eIF4A

2000 [PubMed 10799485])

and transcription factor erythroblastosis virus E26 oncogene homolog 1

CTDP1 Rabbit Polyclonal Antibody, 20ul Human Genome Knockout Libraries POLE4 is a histone-fold proteinThis gene encodes a protein which interacts with the carboxy terminus of the RAP74 subunit of transcription initiation factor TFIIF and functions as a phosphatase that processively dephosphorylates the C terminus of POLR2A (a subunit of RNA polymerase II) making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced

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