CDKN3 Polyclonal Antibody, 50ul[BT-AP07568] Long RNA Synthesis With 10 gels included

With 10 gels included

The amino-terminal region is protease resistant and globular in shape

May play an important role in the pathogenesis of neurogenetic diseases

Defects in this gene result in Senior-Loken syndrome type 5

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CDKN3 Polyclonal Antibody, 50ul[BT-AP07568] Long RNA Synthesis With 10 gels includedThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this