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p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes Defects in this gene are

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p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes Defects in this gene areTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency

This protein is a member of the White subfamily

and six HCF repeats

It is an integral membrane protein functioning as a receptor

This gene was missing from previous genome assemblies

p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes Defects in this gene areTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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