PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance The protein has substantial GAP

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

prolactin and growth hormone

SCF(FBXO33) directs ubiquitination of YBX1 (By similarity)

and has been shown to form dimers/oligomers through its leucine-zipper motif

Some modulators interact directly with the basal complex

PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance The protein has substantial GAPThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene