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PABP3 Polyclonal Antibody, 50ul Molecular Biology The protein encoded by MCM4

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PABP3 Polyclonal Antibody, 50ul Molecular Biology The protein encoded by MCM4PABPC3 encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. PABPC3 is part of a small gene family including three protein coding genes and

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Description

The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication

Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation

The protein encoded by this gene is a serine-threonine kinase| belonging to the glycogen synthase kinase subfamily

Alternate splice variants have been characterized

HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules

PABP3 Polyclonal Antibody, 50ul Molecular Biology The protein encoded by MCM4PABPC3 encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. PABPC3 is part of a small gene family including three protein coding genes and

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