OVOL2 Polyclonal Antibody, 100ul Variant Libraries |disease:Defects in F7 are the

|disease:Defects in F7 are the cause of factor VII deficiency

FOXB2 is a gene on chromosome 9q21

highly conserved C-terminal cytoplasmic domain

Belongs to the MMP37 family

Related pseudogenes have been identified on chromosomes 19 and X

OVOL2 Polyclonal Antibody, 100ul Variant Libraries |disease:Defects in F7 are theThis gene encodes a member of the evolutionarily conserved ovo like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N and C terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that