TOK-1 Polyclonal Antibody, 20ul Mammalian Expression some members of this family

some members of this family may be involved in embryogenesis

represent different pseudogenes

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

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and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers

TOK-1 Polyclonal Antibody, 20ul Mammalian Expression some members of this familyBCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N terminal half shares moderate homology with regions of calmodulin and M calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a