PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Mutations in GJA1 have been

Mutations in GJA1 have been associated with oculodentodigital dysplasia

Transcription factor Dp-2 forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes

Ran-dependent mechanism

It may function as a blood platelet activation marker

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins

PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Mutations in GJA1 have beenMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma