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TLX1 Polyclonal Antibody, 100ul Centrifuges Cofactors B and E can

SKU: 76383611178

4.1
USD123.75 USD146.75

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TLX1 Polyclonal Antibody, 100ul Centrifuges Cofactors B and E canThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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Description

Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers

Mutations in this gene have been associated with Oguchi disease

An important paralog of this gene is RIMKLA

promotes p53/TP53 phosphorylation on ‘Ser-46' and subsequent apoptosis

L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor

TLX1 Polyclonal Antibody, 100ul Centrifuges Cofactors B and E canThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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