NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Translocations with the ETV6 gene

Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia

Activity of this protein is key in the development of neural tissues| particularly the eye

Overexpression of this gene has been shown to induce apoptosis in cells

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

Fascin proteins organize F-actin into parallel bundles

NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Translocations with the ETV6 geneNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four