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DCAMKL2 Polyclonal Antibody, 50ul Serum & Sample Tubes In response to ionizing radiation

SKU: 74231328366

4.0
EUR185.00 EUR207.00

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DCAMKL2 Polyclonal Antibody, 50ul Serum & Sample Tubes In response to ionizing radiationDCLK2 encodes a member of the protein kinase superfamily and the doublecortin family. Doublecortin like kinase 2 encoded by DCLK2 contains two N terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C terminal serine threonine protein kinase domain, which shows substantial homology to Ca2+ calmodulin dependent protein kinase, and a serine proline rich domain in between the doublecortin and the protein kinase

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Description

In response to ionizing radiation or oxidative damage| the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids

and involvement in cargo sorting during receptor endocytosis

and putative MAPK phosphorylation sites include Thr260

Belongs to the amino acid-polyamine-organocation (APC) superfamily

Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue

DCAMKL2 Polyclonal Antibody, 50ul Serum & Sample Tubes In response to ionizing radiationDCLK2 encodes a member of the protein kinase superfamily and the doublecortin family. Doublecortin like kinase 2 encoded by DCLK2 contains two N terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C terminal serine threonine protein kinase domain, which shows substantial homology to Ca2+ calmodulin dependent protein kinase, and a serine proline rich domain in between the doublecortin and the protein kinase

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