TPH2(Phospho Ser19) Polyclonal Antibody, 20ul Cell Culture Dishes Pseudogenes of this gene are

Pseudogenes of this gene are present on chromosomes 1| 3| 9| 12 and 20| and on the X chromosome

Interacts with the Axin complex

it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes

It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity

is approximately 18 kb away

TPH2(Phospho Ser19) Polyclonal Antibody, 20ul Cell Culture Dishes Pseudogenes of this gene areThis gene encodes a member of the pterin dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.