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KLF8 Polyclonal Antibody, 100ul Deep Well Plates |tissue specificity:Present mainly in tissues

SKU: 72693031630

4.7
USD123.75 USD171.75

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KLF8 Polyclonal Antibody, 100ul Deep Well Plates |tissue specificity:Present mainly in tissuesKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.

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Description

|tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium

ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity

Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Bacterial invasion of epithelial cells

serine/threonine protein kinase family

This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins

KLF8 Polyclonal Antibody, 100ul Deep Well Plates |tissue specificity:Present mainly in tissuesKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.

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