GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Knockout studies of the homologous

Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus

Multiple 5' alternatively spliced variants

especially in brain development

while isoform 2 is detected only in lymph nodes

A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis

GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Knockout studies of the homologousThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.