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TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The gene resides on chromosome

SKU: 71593551928

4.3
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TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The gene resides on chromosomeThe protein encoded by this gene forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The encoded protein is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

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The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo

amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection

tissue specificity:Widely expressed with high levels in heart

TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The gene resides on chromosomeThe protein encoded by this gene forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The encoded protein is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

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