DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification They are differentially regulated after

They are differentially regulated after early development

Alström syndrome

Gene Ontology (GO) annotations related to RABEP2 include GTPase activator activity and growth factor activity

and being expressed in vascular endothelium cells and binding to L-selectin

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification They are differentially regulated afterThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras