SUOX Rabbit Polyclonal Antibody, 50ul Vacuum Aspirator Four gamma-crystallin genes (gamma-A through

Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E| gamma-F| gamma-G) are tandemly organized in a genomic segment as a gene cluster

The protein encoded by this gene is the receptor for colony stimulating factor 1

and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain)

Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A

Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36

SUOX Rabbit Polyclonal Antibody, 50ul Vacuum Aspirator Four gamma-crystallin genes (gamma-A throughSulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results