EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter BHLHE41 (basic helix-loop-helix family member

BHLHE41 (basic helix-loop-helix family member e41) encodes a basic helix-loop-helix protein expressed in various tissues

Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis

Mutations in this gene have been associated with pontocerebellar hypoplasia type 2

CLCN4 is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I)

It is the receptor for follicle stimulating hormone and functions in gonad development

EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter BHLHE41 (basic helix-loop-helix family memberThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.