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PGD Polyclonal Antibody, 20ul Deep Well Plates MRE11A encodes a nuclear protein

SKU: 69736407166

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DKK97.20 DKK124.20

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PGD Polyclonal Antibody, 20ul Deep Well Plates MRE11A encodes a nuclear protein6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

MRE11A encodes a nuclear protein involved in homologous recombination

It uses multiple polyadenylation sites

Caspase 8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli

The gene is highly polymorphic in the human population

In vitro studies demonstrated that ERK

PGD Polyclonal Antibody, 20ul Deep Well Plates MRE11A encodes a nuclear protein6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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